increased carcinoma incidence_Espl1<Gt(XL058)Byg>/Espl1<+>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0002038B6129Trp53tm1TyjEspl1GtXL058BygEspl1GtXL058BygEspl1Trp53tm1TyjTrp53Trp53Trp53tm1TyjEspl1Espl1GtXL058Byg

increased carcinoma incidence_Espl1<Gt(XL058)Byg>/Espl1<+>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• extra spindle pole bodies 1, separase
  http://metadb.riken.jp/db/mgi_rdf/MGI:2146156

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Espl1<Gt(XL058)Byg>/Espl1<+>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Trp53<tm1Tyj>|Espl1<+>|Espl1<Gt(XL058)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129-Trp53<tm1Tyj> Espl1<Gt(XL058)Byg>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002038

文献

http://purl.org/net/cito/citesAsAuthority

• Malini. Mukherjee, et.al., Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice., PloS one, 2011, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/21799785