increased carcinoma incidence_Braf<tm1.1Brd>/Braf<+>,Cdkn2a<tm1.1Brn>/Cdkn2a<tm1.1Brn>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0002038I129P2OlaHsd129S7SvEvBrdC57BL6SJLBraftm11BrdBrafCdkn2atm11BrnCdkn2atm11BrnTgVil1cre997Gum0BrafTgVil1cre997GumBraftm11BrdCdkn2atm11Brn

increased carcinoma incidence_Braf<tm1.1Brd>/Braf<+>,Cdkn2a<tm1.1Brn>/Cdkn2a<tm1.1Brn>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957
• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm1.1Brd>/Braf<+>,Cdkn2a<tm1.1Brn>/Cdkn2a<tm1.1Brn>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Braf<+>|Tg(Vil1-cre)997Gum|Braf<tm1.1Brd>|Cdkn2a<tm1.1Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002038

文献

http://purl.org/net/cito/citesAsAuthority

• Roland. Rad, et.al., A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention., Cancer cell, 2013, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/23845441