increased pituitary adenoma incidence_Cdk4<tm1.1Bbd>/Cdk4<+>,Kras<tm1Bbd>/Kras<+>,Tg(CMV-cre)1Cgn/?

http://metadb.riken.jp/0002041I129S1Sv129X1SvJBALBcJC57BL6Cdk4tm11BbdCdk4Krastm1BbdKrasTgCMVcre1CgnKrastm1BbdKrasCdk4tm11BbdTgCMVcre1CgnCdk4

increased pituitary adenoma incidence_Cdk4<tm1.1Bbd>/Cdk4<+>,Kras<tm1Bbd>/Kras<+>,Tg(CMV-cre)1Cgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88357
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176179

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdk4<tm1.1Bbd>/Cdk4<+>,Kras<tm1Bbd>/Kras<+>,Tg(CMV-cre)1Cgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm1Bbd>|Kras<+>|Cdk4<tm1.1Bbd>|Tg(CMV-cre)1Cgn|Cdk4<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pituitary adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002041

文献

http://purl.org/net/cito/citesAsAuthority

• Carmen. Guerra, et.al., Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context., Cancer cell, 2003, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/12957286