increased colonic adenoma incidence_Apc<Min>/Apc<+>,Esr1<tm1.1Mma>/Esr1<+>

http://metadb.riken.jp/0002044I129S2SvPasC57BL6JApcMinApcEsr1tm11MmaEsr1ApcEsr1Esr1tm11MmaApcMin

increased colonic adenoma incidence_Apc<Min>/Apc<+>,Esr1<tm1.1Mma>/Esr1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• estrogen receptor 1 (alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352467
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<+>,Esr1<tm1.1Mma>/Esr1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<+>|Esr1<+>|Esr1<tm1.1Mma>|Apc<Min>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased colonic adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002044

文献

http://purl.org/net/cito/citesAsAuthority

• Nancy L. Cho, et.al., Estrogen receptors alpha and beta are inhibitory modifiers of Apc-dependent tumorigenesis in the proximal colon of Min/+ mice., Cancer research, 2007, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/17332369