increased colonic adenoma incidence_Apc<Min>/Apc<+>,Esr2<tm1Mma>/Esr2<tm1Mma>

http://metadb.riken.jp/0002044I129S2SvPasC57BL6JApcMinApcEsr2tm1MmaEsr2tm1MmaApcEsr2tm1MmaApcMin

increased colonic adenoma incidence_Apc<Min>/Apc<+>,Esr2<tm1Mma>/Esr2<tm1Mma>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• estrogen receptor 2 (beta)
  http://metadb.riken.jp/db/mgi_rdf/MGI:109392

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<+>,Esr2<tm1Mma>/Esr2<tm1Mma>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<+>|Esr2<tm1Mma>|Apc<Min>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased colonic adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002044

文献

http://purl.org/net/cito/citesAsAuthority

• Nancy L. Cho, et.al., Estrogen receptors alpha and beta are inhibitory modifiers of Apc-dependent tumorigenesis in the proximal colon of Min/+ mice., Cancer research, 2007, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/17332369