increased lung adenoma incidence_Kras<tm4Tyj>/Kras<+>,Sftpc<tm1.1(cre/ERT2)Ptch>/Sftpc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0002048I129P2OlaHsd129S4SvJaeC57BL6FVBKrastm4TyjKrasSftpctm11creERT2PtchSftpcTrp53tm1BrnTrp53tm1BrnSftpctm11creERT2PtchSftpcKrasKrastm4TyjTrp53tm1Brn

increased lung adenoma incidence_Kras<tm4Tyj>/Kras<+>,Sftpc<tm1.1(cre/ERT2)Ptch>/Sftpc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• surfactant associated protein C
  http://metadb.riken.jp/db/mgi_rdf/MGI:109517

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Sftpc<tm1.1(cre/ERT2)Ptch>/Sftpc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sftpc<tm1.1(cre/ERT2)Ptch>|Sftpc<+>|Kras<+>|Kras<tm4Tyj>|Trp53<tm1Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002048

文献

http://purl.org/net/cito/citesAsAuthority

• Chuwen. Lin, et.al., Alveolar type II cells possess the capability of initiating lung tumor development., PloS one, 2012, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/23285300