Chuwen. Lin, et.al., Alveolar type II cells possess the capability of initiating lung tumor development., PloS one, 2012, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/23285300

Chuwen. Lin, et.al., Alveolar type II cells possess the capability of initiating lung tumor development., PloS one, 2012, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sftpc<tm1.1(cre/ERT2)Ptch>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5485991
• Tg(Sftpc-rtTA,Nudt18-tetO-cre)1Ptch
  http://metadb.riken.jp/db/mgi_rdf/MGI:5486022

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased lung adenoma incidence_Kras<tm4Tyj>/Kras<+>,Sftpc<tm1.1(cre/ERT2)Ptch>/Sftpc<+>
  http://metadb.riken.jp/0002048I129P2OlaHsdC57BL6FVBKrastm4TyjKrasSftpctm11creERT2PtchSftpcSftpctm11creERT2PtchSftpcKrasKrastm4Tyj
• premature death_Kras<tm4Tyj>/Kras<+>,Sftpc<tm1.1(cre/ERT2)Ptch>/Sftpc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S4SvJaeC57BL6FVBKrastm4TyjKrasSftpctm11creERT2PtchSftpcTrp53tm1BrnTrp53tm1BrnSftpctm11creERT2PtchSftpcKrasKrastm4TyjTrp53tm1Brn
• increased lung adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Sftpc<tm1.1(cre/ERT2)Ptch>/Sftpc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0002027I129P2OlaHsd129S4SvJaeC57BL6FVBKrastm4TyjKrasSftpctm11creERT2PtchSftpcTrp53tm1BrnTrp53tm1BrnSftpctm11creERT2PtchSftpcKrasKrastm4TyjTrp53tm1Brn
• increased type II pneumocyte number_Kras<tm4Tyj>/Kras<+>,Sftpc<tm1.1(cre/ERT2)Ptch>/Sftpc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0010810I129P2OlaHsd129S4SvJaeC57BL6FVBKrastm4TyjKrasSftpctm11creERT2PtchSftpcTrp53tm1BrnTrp53tm1BrnSftpctm11creERT2PtchSftpcKrasKrastm4TyjTrp53tm1Brn
• increased tumor incidence_Tg(Sftpc-rtTA,Nudt18-tetO-cre)1Ptch/0,Tg(tetO-EGFR*L858R)56Hev/0
  http://metadb.riken.jp/0002020IC57BL6CBACD1TgSftpcrtTANudt18tetOcre1Ptch0TgtetOEGFRL858R56Hev0TgtetOEGFRL858R56HevTgSftpcrtTANudt18tetOcre1Ptch
• increased lung adenoma incidence_Kras<tm4Tyj>/Kras<+>,Sftpc<tm1.1(cre/ERT2)Ptch>/Sftpc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0002048I129P2OlaHsd129S4SvJaeC57BL6FVBKrastm4TyjKrasSftpctm11creERT2PtchSftpcTrp53tm1BrnTrp53tm1BrnSftpctm11creERT2PtchSftpcKrasKrastm4TyjTrp53tm1Brn

class

http://purl.org/net/cito/citesAsAuthority

• Sftpc<tm1.1(cre/ERT2)Ptch>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5485991
• Tg(Sftpc-rtTA,Nudt18-tetO-cre)1Ptch
  http://metadb.riken.jp/db/mgi_rdf/MGI:5486022