increased lung adenoma incidence_Braf<tm1Mmcm>/Braf<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

http://metadb.riken.jp/0002048I129P2OlaHsdC57BL6SJLBraftm1MmcmBrafPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdBraftm1MmcmBrafPolr2a

increased lung adenoma incidence_Braf<tm1Mmcm>/Braf<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polymerase (RNA) II (DNA directed) polypeptide A
  http://metadb.riken.jp/db/mgi_rdf/MGI:98086
• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm1Mmcm>/Braf<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Polr2a<tm1(cre/ERT2)Bbd>|Braf<tm1Mmcm>|Braf<+>|Polr2a<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002048

文献

http://purl.org/net/cito/citesAsAuthority

• David. Dankort, et.al., A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors., Genes & development, 2007, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/17299132