David. Dankort, et.al., A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors., Genes & development, 2007, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/17299132

David. Dankort, et.al., A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors., Genes & development, 2007, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Braf<tm1Mmcm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711771

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased lung adenocarcinoma incidence_Braf<tm1Mmcm>/Braf<+>
  http://metadb.riken.jp/0002027I129P2OlaHsdBraftm1MmcmBrafBraftm1MmcmBraf
• increased lung adenoma incidence_Braf<tm1Mmcm>/Braf<+>
  http://metadb.riken.jp/0002048I129P2OlaHsdBraftm1MmcmBrafBraftm1MmcmBraf
• no abnormal phenotype detected_Braf<tm1Mmcm>/Braf<+>
  http://metadb.riken.jp/0002169I129P2OlaHsdBraftm1MmcmBrafBraftm1MmcmBraf
• premature death_Braf<tm1Mmcm>/Braf<+>
  http://metadb.riken.jp/0002083I129P2OlaHsdBraftm1MmcmBrafBraftm1MmcmBraf
• lung epithelium hyperplasia_Braf<tm1Mmcm>/Braf<+>
  http://metadb.riken.jp/0010945I129P2OlaHsdBraftm1MmcmBrafBraftm1MmcmBraf
• increased lung tumor incidence_Braf<tm1Mmcm>/Braf<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0008014I129P2OlaHsdBraftm1MmcmBrafTrp53tm1BrnTrp53tm1BrnBraftm1MmcmTrp53tm1BrnBraf
• increased lung tumor incidence_Braf<tm1Mmcm>/Braf<+>
  http://metadb.riken.jp/0008014I129P2OlaHsdBraftm1MmcmBrafBraftm1MmcmBraf
• increased lung adenocarcinoma incidence_Braf<tm1Mmcm>/Braf<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0002027I129P2OlaHsdBraftm1MmcmBrafTrp53tm1BrnTrp53tm1BrnBraftm1MmcmTrp53tm1BrnBraf
• increased lung adenoma incidence_Braf<tm1Mmcm>/Braf<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002048I129P2OlaHsdC57BL6SJLBraftm1MmcmBrafPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdBraftm1MmcmBrafPolr2a
• abnormal lung morphology_Braf<tm1Mmcm>/Braf<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0001175I129P2OlaHsdBraftm1MmcmBrafTrp53tm1BrnTrp53tm1BrnBraftm1MmcmTrp53tm1BrnBraf
• increased lung tumor incidence_Braf<tm1Mmcm>/Braf<+>,Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>
  http://metadb.riken.jp/0008014I129P2OlaHsdBraftm1MmcmBrafCdkn2atm4RdpCdkn2atm4RdpBrafCdkn2atm4RdpBraftm1Mmcm

class

http://purl.org/net/cito/citesAsAuthority

• Braf<tm1Mmcm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711771