increased lung adenoma incidence_Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>,Kras<tm4Tyj>/Kras<tm4Tyj>

http://metadb.riken.jp/0002048I129S4SvJaeC57BL6FVBNGtROSA26Sortm1MYCERT2GevGtROSA26Sortm1MYCERT2GevKrastm4TyjKrastm4TyjGtROSA26Sortm1MYCERT2GevKrastm4Tyj

increased lung adenoma incidence_Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>,Kras<tm4Tyj>/Kras<tm4Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>,Kras<tm4Tyj>/Kras<tm4Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>|Kras<tm4Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002048

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel J. Murphy, et.al., Distinct thresholds govern Myc's biological output in vivo., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/19061836