Daniel J. Murphy, et.al., Distinct thresholds govern Myc's biological output in vivo., Cancer cell, 2008, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/19061836

Daniel J. Murphy, et.al., Distinct thresholds govern Myc's biological output in vivo., Cancer cell, 2008, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3821930
• Gt(ROSA)26Sor<tm1.1(MYC/ERT2)Gev>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3821931

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased apoptosis_Tg(Ins-MYC/Er)1Gev/0
  http://metadb.riken.jp/0006042IC57BL6CBATgInsMYCEr1Gev0TgInsMYCEr1Gev
• increased cell proliferation_Gt(ROSA)26Sor<tm1.1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1.1(MYC/ERT2)Gev>
  http://metadb.riken.jp/0000351IC57BL6FVBNGtROSA26Sortm11MYCERT2GevGtROSA26Sortm11MYCERT2GevGtROSA26Sortm11MYCERT2Gev
• increased lung tumor incidence_Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>,Kras<tm4Tyj>/Kras<tm4Tyj>
  http://metadb.riken.jp/0008014I129S4SvJaeC57BL6FVBNGtROSA26Sortm1MYCERT2GevGtROSA26Sortm1MYCERT2GevKrastm4TyjKrastm4TyjGtROSA26Sortm1MYCERT2GevKrastm4Tyj
• increased lung adenoma incidence_Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>,Kras<tm4Tyj>/Kras<tm4Tyj>
  http://metadb.riken.jp/0002048I129S4SvJaeC57BL6FVBNGtROSA26Sortm1MYCERT2GevGtROSA26Sortm1MYCERT2GevKrastm4TyjKrastm4TyjGtROSA26Sortm1MYCERT2GevKrastm4Tyj
• increased cell proliferation_Cdkn2a<tm1Cjs>/Cdkn2a<tm1Cjs>,Gt(ROSA)26Sor<tm1.1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1.1(MYC/ERT2)Gev>
  http://metadb.riken.jp/0000351I129X1SvJC57BL6FVBNCdkn2atm1CjsCdkn2atm1CjsGtROSA26Sortm11MYCERT2GevGtROSA26Sortm11MYCERT2GevCdkn2atm1CjsGtROSA26Sortm11MYCERT2Gev
• preneoplasia_Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>
  http://metadb.riken.jp/0002009IC57BL6FVBNGtROSA26Sortm1MYCERT2GevGtROSA26Sortm1MYCERT2GevGtROSA26Sortm1MYCERT2Gev
• increased apoptosis_Gt(ROSA)26Sor<tm1.1(MYC/ERT2)Gev>/Gt(ROSA)26Sor<tm1.1(MYC/ERT2)Gev>
  http://metadb.riken.jp/0006042IC57BL6FVBNGtROSA26Sortm11MYCERT2GevGtROSA26Sortm11MYCERT2GevGtROSA26Sortm11MYCERT2Gev
• increased cell proliferation_Tg(Ins-MYC/Er)1Gev/0
  http://metadb.riken.jp/0000351IC57BL6CBATgInsMYCEr1Gev0TgInsMYCEr1Gev

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(MYC/ERT2)Gev>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3821930
• Gt(ROSA)26Sor<tm1.1(MYC/ERT2)Gev>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3821931