increased skin papilloma incidence_Grhl3<tm1Jane>/Grhl3<+>,Pten<tm1Mak>/Pten<+>

http://metadb.riken.jp/0002051I129P2OlaHsd129S1SvGrhl3tm1JaneGrhl3Ptentm1MakPtenPtentm1MakGrhl3Grhl3tm1JanePten

increased skin papilloma incidence_Grhl3<tm1Jane>/Grhl3<+>,Pten<tm1Mak>/Pten<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• grainyhead-like 3 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655333
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grhl3<tm1Jane>/Grhl3<+>,Pten<tm1Mak>/Pten<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Mak>|Grhl3<+>|Grhl3<tm1Jane>|Pten<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skin papilloma incidence
  http://purl.obolibrary.org/obo/MP_0002051

文献

http://purl.org/net/cito/citesAsAuthority

• Charbel. Darido, et.al., Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis., Cancer cell, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/22094257