decreased tumor incidence_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0002052EI129P2OlaHsd129S2SvPasorI129S1Sv129S2SvPas129X1SvJLig4tm1IcrfLig4tm1IcrfTrp53tm1TyjTrp53Lig4tm1IcrfTrp53Trp53tm1Tyj

decreased tumor incidence_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ligase IV, DNA, ATP-dependent
  http://metadb.riken.jp/db/mgi_rdf/MGI:1335098
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lig4<tm1Icrf>/Lig4<tm1Icrf>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lig4<tm1Icrf>|Trp53<+>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002052

文献

http://purl.org/net/cito/citesAsAuthority

• Kenji E. Orii, et.al., Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16777961