decreased tumor incidence_Egfr<wa2>/Egfr<+>,Nf1<tm1Fcr>/Nf1<+>,Trp53<tm1Brd>/Trp53<+>

http://metadb.riken.jp/0002052I129SSvEv129S7SvEvBrdC57BL6C57BL6JEiC3HHeSnJEgfrwa2EgfrNf1tm1FcrNf1Trp53tm1BrdTrp53Trp53Nf1Nf1tm1FcrEgfrTrp53tm1BrdEgfrwa2

decreased tumor incidence_Egfr<wa2>/Egfr<+>,Nf1<tm1Fcr>/Nf1<+>,Trp53<tm1Brd>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306
• epidermal growth factor receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:95294

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Egfr<wa2>/Egfr<+>,Nf1<tm1Fcr>/Nf1<+>,Trp53<tm1Brd>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Nf1<+>|Nf1<tm1Fcr>|Egfr<+>|Trp53<tm1Brd>|Egfr<wa2>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * C57BL/6JEi * C3H/HeSnJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002052

文献

http://purl.org/net/cito/citesAsAuthority

• Benjamin C. Ling, et.al., Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis., Cancer cell, 2005, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/15652750