Benjamin C. Ling, et.al., Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis., Cancer cell, 2005, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/15652750

Benjamin C. Ling, et.al., Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis., Cancer cell, 2005, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Cnp-EGFR)10Nrat
  http://metadb.riken.jp/db/mgi_rdf/MGI:5485351

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Cnp-EGFR)10Nrat
  http://metadb.riken.jp/db/mgi_rdf/MGI:5485351

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal sciatic nerve morphology_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0002651IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• abnormal Schwann cell morphology_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0001106IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• premature death_Nf1<tm1Fcr>/Nf1<+>,Trp53<tm1Brd>/Trp53<+>
  http://metadb.riken.jp/0002083B6129Trp53tm1BrdNf1tm1FcrNf1tm1FcrNf1Trp53tm1BrdTrp53Trp53tm1BrdTrp53Nf1tm1FcrNf1
• abnormal somatic nervous system morphology_Nf1<tm1Fcr>/Nf1<+>,Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0002752I129SSvEvC57BL6SJLNf1tm1FcrNf1TgCnpEGFR10Nrat0Nf1Nf1tm1FcrTgCnpEGFR10Nrat
• increased malignant triton tumor incidence_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0002033IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• increased mast cell number_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0000324IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• peripheral nervous system degeneration_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0000958IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• increased rhabdomyosarcoma incidence_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0002036IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• increased myelin sheath thickness_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0011730IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• abnormal cranial nerve morphology_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0001056IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• decreased tumor incidence_Egfr<wa2>/Egfr<+>,Nf1<tm1Fcr>/Nf1<+>,Trp53<tm1Brd>/Trp53<+>
  http://metadb.riken.jp/0002052I129SSvEv129S7SvEvBrdC57BL6C57BL6JEiC3HHeSnJEgfrwa2EgfrNf1tm1FcrNf1Trp53tm1BrdTrp53Trp53Nf1Nf1tm1FcrEgfrTrp53tm1BrdEgfrwa2
• abnormal myelin sheath morphology_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0003871IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• increased Schwann cell number_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0010742IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• abnormal nervous system morphology_Nf1<tm1Fcr>/Nf1<+>,Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0003632I129SSvEvC57BL6SJLNf1tm1FcrNf1TgCnpEGFR10Nrat0Nf1Nf1tm1FcrTgCnpEGFR10Nrat
• increased brain tumor incidence_Nf1<tm1Fcr>/Nf1<+>,Trp53<tm1Brd>/Trp53<+>
  http://metadb.riken.jp/0009277B6129Trp53tm1BrdNf1tm1FcrNf1tm1FcrNf1Trp53tm1BrdTrp53Trp53tm1BrdTrp53Nf1tm1FcrNf1
• decreased tumor incidence_Nf1<tm1Fcr>/Nf1<+>,Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0002052I129SSvEvC57BL6SJLNf1tm1FcrNf1TgCnpEGFR10Nrat0Nf1Nf1tm1FcrTgCnpEGFR10Nrat
• increased neurofibroma incidence_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0010314IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• abnormal somatic nervous system morphology_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0002752IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• increased malignant tumor incidence_Nf1<tm1Fcr>/Nf1<+>,Trp53<tm1Brd>/Trp53<+>
  http://metadb.riken.jp/0002018B6129Trp53tm1BrdNf1tm1FcrNf1tm1FcrNf1Trp53tm1BrdTrp53Trp53tm1BrdTrp53Nf1tm1FcrNf1
• abnormal nervous system morphology_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0003632IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat
• increased sarcoma incidence_Nf1<tm1Fcr>/Nf1<+>,Trp53<tm1Brd>/Trp53<+>
  http://metadb.riken.jp/0002032B6129Trp53tm1BrdNf1tm1FcrNf1tm1FcrNf1Trp53tm1BrdTrp53Trp53tm1BrdTrp53Nf1tm1FcrNf1
• abnormal neurite morphology_Tg(Cnp-EGFR)10Nrat/0
  http://metadb.riken.jp/0008415IC57BL6SJLTgCnpEGFR10Nrat0TgCnpEGFR10Nrat