increased circulating insulin level_Gsk3b<tm2Jrw>/Gsk3b<tm2Jrw>,Irs2<tm1Mfw>/Irs2<tm1Mfw>,Tg(Ins2-cre)23Herr/?

http://metadb.riken.jp/0002079I129S1Sv129X1SvJC57BL6JCBAJGsk3btm2JrwGsk3btm2JrwIrs2tm1MfwIrs2tm1MfwTgIns2cre23HerrTgIns2cre23HerrGsk3btm2JrwIrs2tm1Mfw

increased circulating insulin level_Gsk3b<tm2Jrw>/Gsk3b<tm2Jrw>,Irs2<tm1Mfw>/Irs2<tm1Mfw>,Tg(Ins2-cre)23Herr/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334
• transgene insertion 23, Pedro Luis Herrera
  http://metadb.riken.jp/db/mgi_rdf/MGI:4431238
• glycogen synthase kinase 3 beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861437

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gsk3b<tm2Jrw>/Gsk3b<tm2Jrw>,Irs2<tm1Mfw>/Irs2<tm1Mfw>,Tg(Ins2-cre)23Herr/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-cre)23Herr|Gsk3b<tm2Jrw>|Irs2<tm1Mfw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002079

文献

http://purl.org/net/cito/citesAsAuthority

• Katsuya. Tanabe, et.al., Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance., PLoS biology, 2008, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/18288891