increased circulating insulin level_Foxo1<tm2.1Dac>/Foxo1<tm2.1Dac>,Insr<tm1Dac>/Insr<+>

http://metadb.riken.jp/0002079I129S4SvJaeC57BL6Foxo1tm21DacFoxo1tm21DacInsrtm1DacInsrFoxo1tm21DacInsrtm1DacInsr

increased circulating insulin level_Foxo1<tm2.1Dac>/Foxo1<tm2.1Dac>,Insr<tm1Dac>/Insr<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96575
• forkhead box O1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890077

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxo1<tm2.1Dac>/Foxo1<tm2.1Dac>,Insr<tm1Dac>/Insr<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxo1<tm2.1Dac>|Insr<tm1Dac>|Insr<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002079

文献

http://purl.org/net/cito/citesAsAuthority

• Alexander S. Banks, et.al., Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice., Cell metabolism, 2011, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/22055502