increased circulating insulin level_Apob<tm2Sgy>/Apob<tm2Sgy>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>

http://metadb.riken.jp/0002079I129S7SvEvBrdC57BL6Apobtm2SgyApobtm2SgyLdlrtm1HerLdlrtm1HerLepobLepobLepobApobtm2SgyLdlrtm1Her

increased circulating insulin level_Apob<tm2Sgy>/Apob<tm2Sgy>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• apolipoprotein B
  http://metadb.riken.jp/db/mgi_rdf/MGI:88052
• leptin
  http://metadb.riken.jp/db/mgi_rdf/MGI:104663
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apob<tm2Sgy>/Apob<tm2Sgy>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lep<ob>|Apob<tm2Sgy>|Ldlr<tm1Her>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002079

文献

http://purl.org/net/cito/citesAsAuthority

• David J. Lloyd, et.al., Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48-/-Lepob/ob mice devoid of ApoE or Ldlr., American journal of physiology. Endocrinology and metabolism, 2008, 294
  http://rdf.ncbi.nlm.nih.gov/pubmed/18160459