postnatal lethality_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>,Pten<tm1Hwu>/Pten<tm1Hwu>

http://metadb.riken.jp/0002082I129129P2OlaHsd129S4SvJaeBALBcFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnPtentm1HwuPtentm1HwuPtentm1HwuRb1tm2BrnTrp53tm1BrnCalcatm11creERT2PtchCalca

postnatal lethality_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>,Pten<tm1Hwu>/Pten<tm1Hwu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calcitonin/calcitonin-related polypeptide, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:2151253
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>,Pten<tm1Hwu>/Pten<tm1Hwu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Rb1<tm2Brn>|Trp53<tm1Brn>|Calca<tm1.1(cre/ERT2)Ptch>|Calca<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129P2/OlaHsd * 129S4/SvJae * BALB/c * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• postnatal lethality
  http://purl.obolibrary.org/obo/MP_0002082

文献

http://purl.org/net/cito/citesAsAuthority

• Hai. Song, et.al., Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/23047698