Hai. Song, et.al., Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

http://rdf.ncbi.nlm.nih.gov/pubmed/23047698

Hai. Song, et.al., Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Calca<tm1.1(cre/ERT2)Ptch>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5460801

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• postnatal lethality_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0002082I129129P2OlaHsd129S4SvJaeBALBcFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnPtentm1HwuPtentm1HwuPtentm1HwuRb1tm2BrnTrp53tm1BrnCalcatm11creERT2PtchCalca
• increased lung small cell carcinoma incidence_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>
  http://metadb.riken.jp/0008715I129129P2OlaHsdFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnRb1tm2BrnCalcaCalcatm11creERT2PtchTrp53tm1Brn
• increased thyroid tumor incidence_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0010316I129129P2OlaHsd129S4SvJaeBALBcFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnPtentm1HwuPtentm1HwuPtentm1HwuRb1tm2BrnTrp53tm1BrnCalcatm11creERT2PtchCalca
• abnormal pulmonary neuroendocrine body morphology_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>
  http://metadb.riken.jp/0010918I129129P2OlaHsdFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnRb1tm2BrnCalcaCalcatm11creERT2PtchTrp53tm1Brn
• increased metastatic potential_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0001272I129129P2OlaHsd129S4SvJaeBALBcFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnPtentm1HwuPtentm1HwuPtentm1HwuRb1tm2BrnTrp53tm1BrnCalcatm11creERT2PtchCalca
• abnormal pulmonary neuroendocrine body morphology_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0010918I129129P2OlaHsd129S4SvJaeBALBcFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnPtentm1HwuPtentm1HwuPtentm1HwuRb1tm2BrnTrp53tm1BrnCalcatm11creERT2PtchCalca
• abnormal pulmonary neuroendocrine body morphology_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>
  http://metadb.riken.jp/0010918I129P2OlaHsd129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorCalcatm11creERT2PtchCalcaCalcaGtROSA26Sortm1DTAJpmbCalcatm11creERT2PtchGtROSA26Sor
• increased lung small cell carcinoma incidence_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0008715I129129P2OlaHsd129S4SvJaeBALBcFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnPtentm1HwuPtentm1HwuPtentm1HwuRb1tm2BrnTrp53tm1BrnCalcatm11creERT2PtchCalca
• postnatal lethality_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>
  http://metadb.riken.jp/0002082I129129P2OlaHsdFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnRb1tm2BrnCalcaCalcatm11creERT2PtchTrp53tm1Brn
• increased thyroid tumor incidence_Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Rb1<tm2Brn>/Rb1<tm2Brn>
  http://metadb.riken.jp/0010316I129129P2OlaHsdFVBNCalcatm11creERT2PtchCalcaTrp53tm1BrnTrp53tm1BrnRb1tm2BrnRb1tm2BrnRb1tm2BrnCalcaCalcatm11creERT2PtchTrp53tm1Brn
• abnormal Clara cell morphology_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Calca<tm1.1(cre/ERT2)Ptch>/Calca<+>
  http://metadb.riken.jp/0010809I129P2OlaHsd129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorCalcatm11creERT2PtchCalcaCalcaGtROSA26Sortm1DTAJpmbCalcatm11creERT2PtchGtROSA26Sor

class

http://purl.org/net/cito/citesAsAuthority

• Calca<tm1.1(cre/ERT2)Ptch>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5460801