postnatal lethality_Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(KRT5-cre)5132Jlj/0

http://metadb.riken.jp/0002082I129S1Sv129S2SvPas129X1SvJC57BL6Chuktm1YhuChuktm1YhuTnfrsf1atm1MakTnfrsf1atm1MakTgKRT5cre5132Jlj0Tnfrsf1atm1MakTgKRT5cre5132JljChuktm1Yhu

postnatal lethality_Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(KRT5-cre)5132Jlj/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5132, Jose Luis Jorcano
  http://metadb.riken.jp/db/mgi_rdf/MGI:3050066
• tumor necrosis factor receptor superfamily, member 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314884
• conserved helix-loop-helix ubiquitous kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99484

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(KRT5-cre)5132Jlj/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tnfrsf1a<tm1Mak>|Tg(KRT5-cre)5132Jlj|Chuk<tm1Yhu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• postnatal lethality
  http://purl.obolibrary.org/obo/MP_0002082

文献

http://purl.org/net/cito/citesAsAuthority

• Bigang. Liu, et.al., IKKalpha is required to maintain skin homeostasis and prevent skin cancer., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18772111