postnatal lethality_Foxo1<tm1Whb>/Foxo1<+>,Insr<tm1Dac>/Insr<tm1Dac>

http://metadb.riken.jp/0002082I129S4SvJaeC57BL6Foxo1tm1WhbFoxo1Insrtm1DacInsrtm1DacFoxo1Insrtm1DacFoxo1tm1Whb

postnatal lethality_Foxo1<tm1Whb>/Foxo1<+>,Insr<tm1Dac>/Insr<tm1Dac>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96575
• forkhead box O1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890077

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxo1<tm1Whb>/Foxo1<+>,Insr<tm1Dac>/Insr<tm1Dac>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxo1<+>|Insr<tm1Dac>|Foxo1<tm1Whb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• postnatal lethality
  http://purl.obolibrary.org/obo/MP_0002082

文献

http://purl.org/net/cito/citesAsAuthority

• Jun. Nakae, et.al., Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1., Nature genetics, 2002, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/12219087