Jun. Nakae, et.al., Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1., Nature genetics, 2002, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/12219087

Jun. Nakae, et.al., Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1., Nature genetics, 2002, 32

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Foxo1<tm1Whb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447732
• Tg(Ttr-Foxo1)305Dac
  http://metadb.riken.jp/db/mgi_rdf/MGI:3521642
• Tg(Ttr-Foxo1)307Dac
  http://metadb.riken.jp/db/mgi_rdf/MGI:3521643

class

http://purl.org/net/cito/citesAsAuthority

• Foxo1<tm1Whb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447732
• Tg(Ttr-Foxo1)305Dac
  http://metadb.riken.jp/db/mgi_rdf/MGI:3521642
• Tg(Ttr-Foxo1)307Dac
  http://metadb.riken.jp/db/mgi_rdf/MGI:3521643

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hyperglycemia_Tg(Ttr-Foxo1)305Dac/0
  http://metadb.riken.jp/0001559IFVBC57BL6TgTtrFoxo1305Dac0TgTtrFoxo1305Dac
• hyperglycemia_Tg(Ttr-Foxo1)307Dac/0
  http://metadb.riken.jp/0001559IFVBC57BL6TgTtrFoxo1307Dac0TgTtrFoxo1307Dac
• abnormal glucose homeostasis_Insr<tm1Dac>/Insr<tm1Dac>
  http://metadb.riken.jp/0002078I129S4SvJaeC57BL6Insrtm1DacInsrtm1DacInsrtm1Dac
• increased circulating insulin level_Tg(Ttr-Foxo1)307Dac/0
  http://metadb.riken.jp/0002079IFVBC57BL6TgTtrFoxo1307Dac0TgTtrFoxo1307Dac
• postnatal lethality_Foxo1<tm1Whb>/Foxo1<+>,Insr<tm1Dac>/Insr<tm1Dac>
  http://metadb.riken.jp/0002082I129S4SvJaeC57BL6Foxo1tm1WhbFoxo1Insrtm1DacInsrtm1DacFoxo1Insrtm1DacFoxo1tm1Whb
• decreased circulating insulin level_Tg(Ttr-Foxo1)305Dac/0
  http://metadb.riken.jp/0002727IFVBC57BL6TgTtrFoxo1305Dac0TgTtrFoxo1305Dac
他8件を見る
• increased insulin sensitivity_Tg(Ttr-Foxo1)307Dac/0
  http://metadb.riken.jp/0002891IFVBC57BL6TgTtrFoxo1307Dac0TgTtrFoxo1307Dac
• abnormal pancreatic beta cell morphology_Tg(Ttr-Foxo1)305Dac/0
  http://metadb.riken.jp/0005217IFVBC57BL6TgTtrFoxo1305Dac0TgTtrFoxo1305Dac
• abnormal pancreatic beta cell morphology_Tg(Ttr-Foxo1)307Dac/0
  http://metadb.riken.jp/0005217IFVBC57BL6TgTtrFoxo1307Dac0TgTtrFoxo1307Dac
• impaired glucose tolerance_Tg(Ttr-Foxo1)305Dac/0
  http://metadb.riken.jp/0005293IFVBC57BL6TgTtrFoxo1305Dac0TgTtrFoxo1305Dac
• impaired glucose tolerance_Tg(Ttr-Foxo1)307Dac/0
  http://metadb.riken.jp/0005293IFVBC57BL6TgTtrFoxo1307Dac0TgTtrFoxo1307Dac
• insulin resistance_Tg(Ttr-Foxo1)305Dac/0
  http://metadb.riken.jp/0005331IFVBC57BL6TgTtrFoxo1305Dac0TgTtrFoxo1305Dac
• decreased glycogen level_Foxo1<tm1Whb>/Foxo1<+>
  http://metadb.riken.jp/0005439NSFoxo1tm1WhbFoxo1Foxo1tm1WhbFoxo1
• decreased circulating glucose level_Foxo1<tm1Whb>/Foxo1<+>,Insr<tm1Dac>/Insr<tm1Dac>
  http://metadb.riken.jp/0005560I129S4SvJaeC57BL6Foxo1tm1WhbFoxo1Insrtm1DacInsrtm1DacFoxo1Insrtm1DacFoxo1tm1Whb