postnatal lethality_Insig1<tm1.1Mbjg>/Insig1<tm1.1Mbjg>,Insig2<tm1Mbjg>/Insig2<+>

http://metadb.riken.jp/0002082I129S6SvEvTacC57BL6NCrlFVBNInsig1tm11MbjgInsig1tm11MbjgInsig2tm1MbjgInsig2Insig2tm1MbjgInsig2Insig1tm11Mbjg

postnatal lethality_Insig1<tm1.1Mbjg>/Insig1<tm1.1Mbjg>,Insig2<tm1Mbjg>/Insig2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin induced gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920249
• insulin induced gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916289

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Insig1<tm1.1Mbjg>/Insig1<tm1.1Mbjg>,Insig2<tm1Mbjg>/Insig2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Insig2<tm1Mbjg>|Insig2<+>|Insig1<tm1.1Mbjg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• postnatal lethality
  http://purl.obolibrary.org/obo/MP_0002082

文献

http://purl.org/net/cito/citesAsAuthority

• Luke J. Engelking, et.al., Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins., The Journal of clinical investigation, 2005, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/16100574