premature death_Col1a1<tm2(tetO-IDH2*R140Q)Ppp>/Col1a1<tm2(tetO-IDH2*R140Q)Ppp>,Flt3<tm1.1Dosm>/Flt3<tm1.1Dosm>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

http://metadb.riken.jp/0002083I129C57BL6Col1a1tm2tetOIDH2R140QPppCol1a1tm2tetOIDH2R140QPppFlt3tm11DosmFlt3tm11DosmGtROSA26Sortm1rtTAM2JaeCol1a1tm2tetOIDH2R140QPppFlt3tm11DosmGtROSA26Sortm1rtTAM2Jae

premature death_Col1a1<tm2(tetO-IDH2*R140Q)Ppp>/Col1a1<tm2(tetO-IDH2*R140Q)Ppp>,Flt3<tm1.1Dosm>/Flt3<tm1.1Dosm>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• FMS-like tyrosine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95559

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm2(tetO-IDH2*R140Q)Ppp>/Col1a1<tm2(tetO-IDH2*R140Q)Ppp>,Flt3<tm1.1Dosm>/Flt3<tm1.1Dosm>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col1a1<tm2(tetO-IDH2*R140Q)Ppp>|Flt3<tm1.1Dosm>|Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Lev M. Kats, et.al., Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance., Cell stem cell, 2014, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/24440599