premature death_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Zuk>

http://metadb.riken.jp/0002083I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm2RobSmad5tm1HuySmad5tm1ZukSmad5tm1ZukAmhr2Smad5tm1HuyAmhr2tm3creBhrSmad1tm2Rob

premature death_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Zuk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SMAD family member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109452
• SMAD family member 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328787
• anti-Mullerian hormone type 2 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:105062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Zuk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smad5<tm1Zuk>|Amhr2<+>|Smad5<tm1Huy>|Amhr2<tm3(cre)Bhr>|Smad1<tm2Rob>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Brooke S. Middlebrook, et.al., Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors., Endocrinology, 2009, 150
  http://rdf.ncbi.nlm.nih.gov/pubmed/19819941