Brooke S. Middlebrook, et.al., Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors., Endocrinology, 2009, 150

http://rdf.ncbi.nlm.nih.gov/pubmed/19819941

Brooke S. Middlebrook, et.al., Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors., Endocrinology, 2009, 150

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• suppressed circulating follicle stimulating hormone level_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>
  http://metadb.riken.jp/0001749I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm2RobSmad5tm1HuySmad5tm1HuySmad1tm2RobAmhr2tm3creBhrAmhr2Smad5tm1Huy
• suppressed circulating follicle stimulating hormone level_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2.1Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>
  http://metadb.riken.jp/0001749I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm21RobSmad5tm1HuySmad5tm1HuyAmhr2tm3creBhrSmad1tm2RobSmad5tm1HuyAmhr2Smad1tm21Rob
• premature death_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2.1Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>
  http://metadb.riken.jp/0002083I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm21RobSmad5tm1HuySmad5tm1HuyAmhr2tm3creBhrSmad1tm2RobSmad5tm1HuyAmhr2Smad1tm21Rob
• premature death_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Zuk>
  http://metadb.riken.jp/0002083I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm2RobSmad5tm1HuySmad5tm1ZukSmad5tm1ZukAmhr2Smad5tm1HuyAmhr2tm3creBhrSmad1tm2Rob
• increased granulosa cell tumor incidence_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2.1Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>
  http://metadb.riken.jp/0012411I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm21RobSmad5tm1HuySmad5tm1HuyAmhr2tm3creBhrSmad1tm2RobSmad5tm1HuyAmhr2Smad1tm21Rob
• premature death_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>
  http://metadb.riken.jp/0002083I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm2RobSmad5tm1HuySmad5tm1HuySmad1tm2RobAmhr2tm3creBhrAmhr2Smad5tm1Huy
• increased granulosa cell tumor incidence_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Zuk>
  http://metadb.riken.jp/0012411I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm2RobSmad5tm1HuySmad5tm1ZukSmad5tm1ZukAmhr2Smad5tm1HuyAmhr2tm3creBhrSmad1tm2Rob
• increased granulosa cell tumor incidence_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>
  http://metadb.riken.jp/0012411I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm2RobSmad5tm1HuySmad5tm1HuySmad1tm2RobAmhr2tm3creBhrAmhr2Smad5tm1Huy
• suppressed circulating follicle stimulating hormone level_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2Rob>,Smad5<tm1Huy>/Smad5<tm1Zuk>
  http://metadb.riken.jp/0001749I129P2OlaHsd129SSvEvC57BL6JAmhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm2RobSmad5tm1HuySmad5tm1ZukSmad5tm1ZukAmhr2Smad5tm1HuyAmhr2tm3creBhrSmad1tm2Rob