premature death_Msh2<tm1Htr>/Msh2<tm1Htr>,Smug1<tm1a(EUCOMM)Hmgu>/Smug1<tm1a(EUCOMM)Hmgu>,Ung<tm1Tld>/Ung<tm1Tld>

http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6C57BL6NMsh2tm1HtrMsh2tm1HtrSmug1tm1aEUCOMMHmguSmug1tm1aEUCOMMHmguUngtm1TldUngtm1TldSmug1tm1aEUCOMMHmguUngtm1TldMsh2tm1Htr

premature death_Msh2<tm1Htr>/Msh2<tm1Htr>,Smug1<tm1a(EUCOMM)Hmgu>/Smug1<tm1a(EUCOMM)Hmgu>,Ung<tm1Tld>/Ung<tm1Tld>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mutS homolog 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:101816
• uracil DNA glycosylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:109352
• single-strand selective monofunctional uracil DNA glycosylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1918976

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Msh2<tm1Htr>/Msh2<tm1Htr>,Smug1<tm1a(EUCOMM)Hmgu>/Smug1<tm1a(EUCOMM)Hmgu>,Ung<tm1Tld>/Ung<tm1Tld>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smug1<tm1a(EUCOMM)Hmgu>|Ung<tm1Tld>|Msh2<tm1Htr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Kristin. Kemmerich, et.al., Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice., Nucleic acids research, 2012, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/22447450