premature death_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Emu-Zfp521)#Homy/0,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6CBATcf3tm1TCF3HLFHomyTcf3TgEmuZfp521Homy0TgMx1cre1Cgn0Tcf3TgEmuZfp521HomyTcf3tm1TCF3HLFHomyTgMx1cre1Cgn

premature death_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Emu-Zfp521)#Homy/0,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transcription factor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:98510
• transgene insertion, Hiroaki Honda
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458206
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Emu-Zfp521)#Homy/0,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tcf3<+>|Tg(Emu-Zfp521)#Homy|Tcf3<tm1(TCF3/HLF)Homy>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• N. Yamasaki, et.al., Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia., Oncogene, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20062079