N. Yamasaki, et.al., Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia., Oncogene, 2010, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/20062079

N. Yamasaki, et.al., Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia., Oncogene, 2010, 29

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tcf3<tm1(TCF3/HLF)Homy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458115
• Tg(Emu-Zfp521)#Homy
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458205

class

http://purl.org/net/cito/citesAsAuthority

• Tcf3<tm1(TCF3/HLF)Homy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458115
• Tg(Emu-Zfp521)#Homy
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458205

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased incidence of induced tumors_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002021I129P2OlaHsdC57BL6CBATcf3tm1TCF3HLFHomyTcf3TgMx1cre1Cgn0Tcf3Tcf3tm1TCF3HLFHomyTgMx1cre1Cgn
• increased leukemia incidence_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Emu-Zfp521)#Homy/0,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002026I129P2OlaHsdC57BL6CBATcf3tm1TCF3HLFHomyTcf3TgEmuZfp521Homy0TgMx1cre1Cgn0Tcf3TgEmuZfp521HomyTcf3tm1TCF3HLFHomyTgMx1cre1Cgn
• premature death_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Emu-Zfp521)#Homy/0,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6CBATcf3tm1TCF3HLFHomyTcf3TgEmuZfp521Homy0TgMx1cre1Cgn0Tcf3TgEmuZfp521HomyTcf3tm1TCF3HLFHomyTgMx1cre1Cgn
• abnormal B cell differentiation_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002144I129P2OlaHsdC57BL6CBATcf3tm1TCF3HLFHomyTcf3TgMx1cre1Cgn0Tcf3Tcf3tm1TCF3HLFHomyTgMx1cre1Cgn
• abnormal B cell differentiation_Tg(Emu-Zfp521)#Homy/0
  http://metadb.riken.jp/0002144NSTgEmuZfp521Homy0TgEmuZfp521Homy
• increased B cell number_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005014I129P2OlaHsdC57BL6CBATcf3tm1TCF3HLFHomyTcf3TgMx1cre1Cgn0Tcf3Tcf3tm1TCF3HLFHomyTgMx1cre1Cgn
他3件を見る
• increased B cell number_Tg(Emu-Zfp521)#Homy/0
  http://metadb.riken.jp/0005014NSTgEmuZfp521Homy0TgEmuZfp521Homy
• abnormal thrombosis_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005048I129P2OlaHsdC57BL6CBATcf3tm1TCF3HLFHomyTcf3TgMx1cre1Cgn0Tcf3Tcf3tm1TCF3HLFHomyTgMx1cre1Cgn
• increased sensitivity to induced morbidity/mortality_Tcf3<tm1(TCF3/HLF)Homy>/Tcf3<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0009763I129P2OlaHsdC57BL6CBATcf3tm1TCF3HLFHomyTcf3TgMx1cre1Cgn0Tcf3Tcf3tm1TCF3HLFHomyTgMx1cre1Cgn