premature death_Pten<tm1Mro>/Pten<tm1Mro>,Tg(KRT14-cre)8Brn/0,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6DBA2DBA2JFVBNPtentm1MroPtentm1MroTgKRT14cre8Brn0Trp53tm1BrnTrp53tm1BrnTrp53tm1BrnTgKRT14cre8BrnPtentm1Mro

premature death_Pten<tm1Mro>/Pten<tm1Mro>,Tg(KRT14-cre)8Brn/0,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 8, Anton Berns
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177242

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Mro>/Pten<tm1Mro>,Tg(KRT14-cre)8Brn/0,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Tg(KRT14-cre)8Brn|Pten<tm1Mro>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Marta. Moral, et.al., Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19176372