premature death_Gli1<tm3(cre/ERT2)Alj>/Gli1<+>,Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>

http://metadb.riken.jp/0002083I129S6SvEvTac129X1SvJGli1tm3creERT2AljGli1GtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcGli1Gli1tm3creERT2Alj

premature death_Gli1<tm3(cre/ERT2)Alj>/Gli1<+>,Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• GLI-Kruppel family member GLI1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95727

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gli1<tm3(cre/ERT2)Alj>/Gli1<+>,Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>|Gli1<+>|Gli1<tm3(cre/ERT2)Alj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Ulrich. Schüller, et.al., Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18691547