Ulrich. Schüller, et.al., Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma., Cancer cell, 2008, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/18691547

Ulrich. Schüller, et.al., Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma., Cancer cell, 2008, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Olig2<tm2(TVA,cre)Rth>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810299

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Atoh1-cre/Esr1*)14Fsh/0
  http://metadb.riken.jp/0002083I129X1SvJFVBNGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTgAtoh1creEsr114Fsh0TgAtoh1creEsr114FshGtROSA26Sortm1SmoEYFPAmc
• increased medulloblastoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0006283I129X1SvJFVBNGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTgGFAPcre25Mes0GtROSA26Sortm1SmoEYFPAmcTgGFAPcre25Mes
• abnormal cerebellum external granule cell layer morphology_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Atoh1-cre/Esr1*)14Fsh/0
  http://metadb.riken.jp/0000872I129X1SvJFVBNGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTgAtoh1creEsr114Fsh0TgAtoh1creEsr114FshGtROSA26Sortm1SmoEYFPAmc
• premature death_Gli1<tm3(cre/ERT2)Alj>/Gli1<+>,Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>
  http://metadb.riken.jp/0002083I129S6SvEvTac129X1SvJGli1tm3creERT2AljGli1GtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcGli1Gli1tm3creERT2Alj
• increased medulloblastoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Atoh1-cre/Esr1*)14Fsh/0
  http://metadb.riken.jp/0006283I129X1SvJFVBNGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTgAtoh1creEsr114Fsh0TgAtoh1creEsr114FshGtROSA26Sortm1SmoEYFPAmc
• premature death_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Olig2<tm2(TVA,cre)Rth>/Olig2<+>
  http://metadb.riken.jp/0002083I129129X1SvJGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcOlig2tm2TVAcreRthOlig2Olig2tm2TVAcreRthOlig2GtROSA26Sortm1SmoEYFPAmc
• increased medulloblastoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tlx3<tm1(cre)Qima>/Tlx3<+>
  http://metadb.riken.jp/0006283I129X1SvJGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTlx3tm1creQimaTlx3GtROSA26Sortm1SmoEYFPAmcTlx3tm1creQimaTlx3
• premature death_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0002083I129X1SvJFVBNGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTgGFAPcre25Mes0GtROSA26Sortm1SmoEYFPAmcTgGFAPcre25Mes
• increased medulloblastoma incidence_Gli1<tm3(cre/ERT2)Alj>/Gli1<+>,Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>
  http://metadb.riken.jp/0006283I129S6SvEvTac129X1SvJGli1tm3creERT2AljGli1GtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcGli1Gli1tm3creERT2Alj
• increased medulloblastoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Olig2<tm2(TVA,cre)Rth>/Olig2<+>
  http://metadb.riken.jp/0006283I129129X1SvJGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcOlig2tm2TVAcreRthOlig2Olig2tm2TVAcreRthOlig2GtROSA26Sortm1SmoEYFPAmc
• premature death_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tlx3<tm1(cre)Qima>/Tlx3<+>
  http://metadb.riken.jp/0002083I129X1SvJGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTlx3tm1creQimaTlx3GtROSA26Sortm1SmoEYFPAmcTlx3tm1creQimaTlx3

class

http://purl.org/net/cito/citesAsAuthority

• Olig2<tm2(TVA,cre)Rth>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810299