premature death_Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0002083I129S7SvEvBrdC57BL6Trp53tm1BrdTrp53tm1BrdTrp53tm1Brd

premature death_Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Hoseok. Song, et.al., p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM., Nature cell biology, 2007, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/17417627
• L A. Donehower, et.al., Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours., Nature, 1992, 356
  http://rdf.ncbi.nlm.nih.gov/pubmed/1552940