Hoseok. Song, et.al., p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM., Nature cell biology, 2007, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/17417627

Hoseok. Song, et.al., p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM., Nature cell biology, 2007, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm5Xu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762531
• Trp53<tm4Xu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762530

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cell cycle checkpoint function_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0004045I129S7SvEvBrdC57BL6Trp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• increased sarcoma incidence_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002032I129S7SvEvBrdC57BL6Trp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• spontaneous chromosome breakage_Trp53<tm5Xu>/Trp53<tm5Xu>
  http://metadb.riken.jp/0004029NSTrp53tm5XuTrp53tm5XuTrp53tm5Xu
• decreased apoptosis_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0006043I129S7SvEvBrdC57BL6Trp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• increased T cell derived lymphoma incidence_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002024I129S7SvEvBrdC57BL6Trp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• increased T cell derived lymphoma incidence_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0002024NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu
• decreased apoptosis_Trp53<tm5Xu>/Trp53<tm5Xu>
  http://metadb.riken.jp/0006043NSTrp53tm5XuTrp53tm5XuTrp53tm5Xu
• decreased apoptosis_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0006043NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu
• premature death_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0002083NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu
• premature death_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002083I129S7SvEvBrdC57BL6Trp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• increased lymphoma incidence_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0012431NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu
• abnormal tumor incidence_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0002019NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu
• spontaneous chromosome breakage_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0004029NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu
• increased tumor incidence_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0002020NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu
• abnormal cell cycle checkpoint function_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0004045NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu
• increased sarcoma incidence_Trp53<tm4Xu>/Trp53<tm4Xu>
  http://metadb.riken.jp/0002032NSTrp53tm4XuTrp53tm4XuTrp53tm4Xu

class

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm5Xu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762531
• Trp53<tm4Xu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762530

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased T cell derived lymphoma incidence in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010220
• abnormal cell cycle checkpoint function in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010887
• decreased apoptosis in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010888
• premature death in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010886