premature death_Nf1<tm1Fcr>/Nf1<+>,Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)#Gtm/0

http://metadb.riken.jp/0002083I129SSvEv129S4SvJaeC57BL6CBANf1tm1FcrNf1Tsc1tm1DjkTsc1tm1DjkTgGFAPcreGtm0Nf1tm1FcrNf1Tsc1tm1DjkTgGFAPcreGtm

premature death_Nf1<tm1Fcr>/Nf1<+>,Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)#Gtm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tuberous sclerosis 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929183
• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306
• transgene insertion #, David H Gutmann
  http://metadb.riken.jp/db/mgi_rdf/MGI:3696795

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nf1<tm1Fcr>/Nf1<+>,Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)#Gtm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nf1<tm1Fcr>|Nf1<+>|Tsc1<tm1Djk>|Tg(GFAP-cre)#Gtm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Sutapa. Banerjee, et.al., Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21896734