premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)470Fgh/0

http://metadb.riken.jp/0002083I129SvC57BL6JCBASJLCdkn2atm1RdpCdkn2atm1RdpTgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470FghCdkn2atm1Rdp

premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)470Fgh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 470, Frank G Haluska
  http://metadb.riken.jp/db/mgi_rdf/MGI:4354189

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)470Fgh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tyr-BRAF*V600E)470Fgh|Cdkn2a<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• V K. Goel, et.al., Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice., Oncogene, 2009, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/19398955