V K. Goel, et.al., Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice., Oncogene, 2009, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/19398955

V K. Goel, et.al., Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice., Oncogene, 2009, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Tyr-BRAF*V600E)470Fgh
  http://metadb.riken.jp/db/mgi_rdf/MGI:4354192
• Tg(Tyr-BRAF*V600E)476Fgh
  http://metadb.riken.jp/db/mgi_rdf/MGI:4354193

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Tyr-BRAF*V600E)470Fgh
  http://metadb.riken.jp/db/mgi_rdf/MGI:4354192
• Tg(Tyr-BRAF*V600E)476Fgh
  http://metadb.riken.jp/db/mgi_rdf/MGI:4354193

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)476Fgh/0
  http://metadb.riken.jp/0002083I129SvC57BL6JCBASJLCdkn2atm1RdpCdkn2atm1RdpTgTyrBRAFV600E476Fgh0Cdkn2atm1RdpTgTyrBRAFV600E476Fgh
• hyperpigmentation_Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0001188IC57BL6JCBATgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470Fgh
• increased melanoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0010275I129SvC57BL6JCBASJLCdkn2atm1RdpCdkn2atm1RdpTgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470FghCdkn2atm1Rdp
• abnormal melanocyte morphology_Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0002877IC57BL6JCBATgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470Fgh
• microphthalmia_Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0001297IC57BL6JCBATgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470Fgh
• paralysis_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0000753I129SvC57BL6JCBASJLCdkn2atm1RdpCdkn2atm1RdpTgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470FghCdkn2atm1Rdp
• hydroencephaly_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0001891I129SvC57BL6JCBASJLCdkn2atm1RdpCdkn2atm1RdpTgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470FghCdkn2atm1Rdp
• abnormal melanocyte morphology_Tg(Tyr-BRAF*V600E)476Fgh/0
  http://metadb.riken.jp/0002877IC57BL6JCBATgTyrBRAFV600E476Fgh0TgTyrBRAFV600E476Fgh
• premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0002083I129SvC57BL6JCBASJLCdkn2atm1RdpCdkn2atm1RdpTgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470FghCdkn2atm1Rdp
• premature death_Tg(Tyr-BRAF*V600E)476Fgh/0
  http://metadb.riken.jp/0002083IC57BL6JCBATgTyrBRAFV600E476Fgh0TgTyrBRAFV600E476Fgh
• thick tail_Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0000588IC57BL6JCBATgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470Fgh
• increased melanoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-BRAF*V600E)476Fgh/0
  http://metadb.riken.jp/0010275I129SvC57BL6JCBASJLCdkn2atm1RdpCdkn2atm1RdpTgTyrBRAFV600E476Fgh0Cdkn2atm1RdpTgTyrBRAFV600E476Fgh
• premature death_Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0002083IC57BL6JCBATgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470Fgh
• diluted coat color_Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0000371IC57BL6JCBATgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470Fgh
• increased malignant tumor incidence_Tg(Tyr-BRAF*V600E)476Fgh/0
  http://metadb.riken.jp/0002018IC57BL6JCBATgTyrBRAFV600E476Fgh0TgTyrBRAFV600E476Fgh
• increased malignant tumor incidence_Tg(Tyr-BRAF*V600E)470Fgh/0
  http://metadb.riken.jp/0002018IC57BL6JCBATgTyrBRAFV600E470Fgh0TgTyrBRAFV600E470Fgh