premature death_Tg(Camk2a-IDE)1Selk/0,Tg(PDGFB-APPSwInd)20Lms/0

http://metadb.riken.jp/0002083IC57BL6DBA2TgCamk2aIDE1Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aIDE1Selk

premature death_Tg(Camk2a-IDE)1Selk/0,Tg(PDGFB-APPSwInd)20Lms/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Dennis J Selkoe
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043427
• transgene insertion 20, Lennart Mucke
  http://metadb.riken.jp/db/mgi_rdf/MGI:3057146

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Camk2a-IDE)1Selk/0,Tg(PDGFB-APPSwInd)20Lms/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(PDGFB-APPSwInd)20Lms|Tg(Camk2a-IDE)1Selk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Malcolm A. Leissring, et.al., Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death., Neuron, 2003, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/14687544