Malcolm A. Leissring, et.al., Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death., Neuron, 2003, 40

http://rdf.ncbi.nlm.nih.gov/pubmed/14687544

Malcolm A. Leissring, et.al., Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death., Neuron, 2003, 40

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Camk2a-MME)3Selk
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043425
• Tg(Camk2a-IDE)1Selk
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043428

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• amyloid beta deposits_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003329IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• astrocytosis_Tg(Camk2a-IDE)1Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgCamk2aIDE1Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aIDE1Selk
• amyloid beta deposits_Tg(Camk2a-MME)3Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003329IC57BL6DBA2TgCamk2aMME3Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aMME3Selk
• gliosis_Tg(Camk2a-MME)3Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002183IC57BL6DBA2TgCamk2aMME3Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aMME3Selk
• premature death_Tg(Camk2a-IDE)1Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgCamk2aIDE1Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aIDE1Selk
• no abnormal phenotype detected_Tg(Camk2a-IDE)1Selk/0
  http://metadb.riken.jp/0002169IC57BL6TgCamk2aIDE1Selk0TgCamk2aIDE1Selk
• no abnormal phenotype detected_Tg(Camk2a-MME)3Selk/0
  http://metadb.riken.jp/0002169IC57BL6TgCamk2aMME3Selk0TgCamk2aMME3Selk
• premature death_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• astrocytosis_Tg(Camk2a-MME)3Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgCamk2aMME3Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aMME3Selk
• abnormal neurite morphology_Tg(Camk2a-MME)3Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0008415IC57BL6DBA2TgCamk2aMME3Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aMME3Selk
• amyloid beta deposits_Tg(Camk2a-IDE)1Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003329IC57BL6DBA2TgCamk2aIDE1Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aIDE1Selk
• gliosis_Tg(Camk2a-IDE)1Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002183IC57BL6DBA2TgCamk2aIDE1Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aIDE1Selk
• abnormal neurite morphology_Tg(Camk2a-IDE)1Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0008415IC57BL6DBA2TgCamk2aIDE1Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aIDE1Selk
• premature death_Tg(Camk2a-MME)3Selk/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgCamk2aMME3Selk0TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20LmsTgCamk2aMME3Selk

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Camk2a-MME)3Selk
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043425
• Tg(Camk2a-IDE)1Selk
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043428