abnormal limb bone morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>

http://metadb.riken.jp/0002115I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor

abnormal limb bone morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• cholinergic receptor, nicotinic, alpha polypeptide 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:99779

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chrna7<tm2.1(cre)Swr>|Gt(ROSA)26Sor<tm1(DTA)Mrc>|Chrna7<+>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal limb bone morphology
  http://purl.obolibrary.org/obo/MP_0002115

文献

http://purl.org/net/cito/citesAsAuthority

• Scott W. Rogers, et.al., Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure., American journal of medical genetics. Part A, 2012, 158A
  http://rdf.ncbi.nlm.nih.gov/pubmed/22473653