Scott W. Rogers, et.al., Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure., American journal of medical genetics. Part A, 2012, 158A

http://rdf.ncbi.nlm.nih.gov/pubmed/22473653

Scott W. Rogers, et.al., Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure., American journal of medical genetics. Part A, 2012, 158A

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Chrna7<tm1.1Swr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5662226
• Chrna7<tm2.1(cre)Swr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5662228

class

http://purl.org/net/cito/citesAsAuthority

• Chrna7<tm1.1Swr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5662226
• Chrna7<tm2.1(cre)Swr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5662228

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal rostral-caudal axis patterning_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0005221I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• abnormal tooth morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0002100I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• abnormal abdominal wall morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0003257I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• hunched posture_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0001505I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• short mandible_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0000088I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• abnormal craniofacial morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0000428I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• abnormal limb bone morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0002115I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• perinatal lethality, complete penetrance_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0011089I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• abnormal dorsal root ganglion morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0000961I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• enlarged liver_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0000599I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• spina bifida_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0003054I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• omphalocele_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0003052I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• dorsal root ganglion hypoplasia_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0006408I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• flat head_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0012174I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• abnormal retinal pigment epithelium morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0005201I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• enlarged pancreas_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0003450I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• delayed caudal neuropore closure_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0012709I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• anemia_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0001577I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• enlarged salivary gland_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0009516I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor
• abnormal tail morphology_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>
  http://metadb.riken.jp/0002111I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor