abnormal B cell differentiation_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>

http://metadb.riken.jp/0002144I129S7SvEvBrdC57BL6JIgktm1DhuIgktm1DhuIglc1tm2UstIglc1tm2UstIglc1tm2UstIgktm1Dhu

abnormal B cell differentiation_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin lambda constant 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99546
• immunoglobulin kappa chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96494

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Iglc1<tm2Ust>|Igk<tm1Dhu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal B cell differentiation
  http://purl.obolibrary.org/obo/MP_0002144

文献

http://purl.org/net/cito/citesAsAuthority

• Tianhe. Sun, et.al., A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling., Immunity, 2002, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/11869685