Tianhe. Sun, et.al., A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling., Immunity, 2002, 16

http://rdf.ncbi.nlm.nih.gov/pubmed/11869685

Tianhe. Sun, et.al., A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling., Immunity, 2002, 16

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Iglc1<tm2Ust>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2657246

class

http://purl.org/net/cito/citesAsAuthority

• Iglc1<tm2Ust>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2657246

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased transitional stage T2 B cell number_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>
  http://metadb.riken.jp/0009926I129S7SvEvBrdC57BL6JIgktm1DhuIgktm1DhuIglc1tm2UstIglc1tm2UstIglc1tm2UstIgktm1Dhu
• decreased mature B cell number_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>
  http://metadb.riken.jp/0008211I129S7SvEvBrdC57BL6JIgktm1DhuIgktm1DhuIglc1tm2UstIglc1tm2UstIglc1tm2UstIgktm1Dhu
• decreased transitional stage T1 B cell number_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>
  http://metadb.riken.jp/0009923I129S7SvEvBrdC57BL6JIgktm1DhuIgktm1DhuIglc1tm2UstIglc1tm2UstIglc1tm2UstIgktm1Dhu
• decreased B cell number_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>
  http://metadb.riken.jp/0005017I129S7SvEvBrdC57BL6JIgktm1DhuIgktm1DhuIglc1tm2UstIglc1tm2UstIglc1tm2UstIgktm1Dhu
• decreased marginal zone B cell number_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>
  http://metadb.riken.jp/0008182I129S7SvEvBrdC57BL6JIgktm1DhuIgktm1DhuIglc1tm2UstIglc1tm2UstIglc1tm2UstIgktm1Dhu
• decreased immature B cell number_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>
  http://metadb.riken.jp/0008215I129S7SvEvBrdC57BL6JIgktm1DhuIgktm1DhuIglc1tm2UstIglc1tm2UstIglc1tm2UstIgktm1Dhu
• abnormal immunoglobulin light chain V-J recombination_Iglc1<tm2Ust>/Iglc1<+>
  http://metadb.riken.jp/0008761I129S7SvEvBrdC57BL6JIglc1tm2UstIglc1Iglc1tm2UstIglc1
• abnormal B cell differentiation_Igk<tm1Dhu>/Igk<tm1Dhu>,Iglc1<tm2Ust>/Iglc1<tm2Ust>
  http://metadb.riken.jp/0002144I129S7SvEvBrdC57BL6JIgktm1DhuIgktm1DhuIglc1tm2UstIglc1tm2UstIglc1tm2UstIgktm1Dhu