abnormal T cell differentiation_Notch1<tm1Agt>/Notch1<tm1Agt>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0002145I129C57BL6CBANotch1tm1AgtNotch1tm1AgtTgMx1cre1Cgn0TgMx1cre1CgnNotch1tm1Agt

abnormal T cell differentiation_Notch1<tm1Agt>/Notch1<tm1Agt>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• notch 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97363

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Notch1<tm1Agt>/Notch1<tm1Agt>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Notch1<tm1Agt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell differentiation
  http://purl.obolibrary.org/obo/MP_0002145

文献

http://purl.org/net/cito/citesAsAuthority

• Valerie. Besseyrias, et.al., Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/17261636
• F. Radtke, et.al., Deficient T cell fate specification in mice with an induced inactivation of Notch1., Immunity, 1999, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/10367900