abnormal T cell differentiation_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(DO11.10)10Dlo/0,Tg(Lck-cre)1Jtak/0

http://metadb.riken.jp/0002145I129C57BL6Grb2tm11HuaGrb2tm11HuaTgDO111010Dlo0TgLckcre1Jtak0TgLckcre1JtakGrb2tm11HuaTgDO111010Dlo

abnormal T cell differentiation_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(DO11.10)10Dlo/0,Tg(Lck-cre)1Jtak/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Junji Takeda
  http://metadb.riken.jp/db/mgi_rdf/MGI:3655253
• transgene insertion 10, Dennis Y Loh
  http://metadb.riken.jp/db/mgi_rdf/MGI:2664401
• growth factor receptor bound protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95805

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(DO11.10)10Dlo/0,Tg(Lck-cre)1Jtak/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)1Jtak|Grb2<tm1.1Hua>|Tg(DO11.10)10Dlo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell differentiation
  http://purl.obolibrary.org/obo/MP_0002145

文献

http://purl.org/net/cito/citesAsAuthority

• Ihn Kyung. Jang, et.al., Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20498059