abnormal T cell differentiation_Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0

http://metadb.riken.jp/0002145I129S1Sv129X1SvJC57BL6CBAGtROSA26Sortm4ACTBtdTomatoEGFPLuoGtROSA26SorHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0GtROSA26SorHnrnpltm11TmoTgLckcre548JxmGtROSA26Sortm4ACTBtdTomatoEGFPLuo

abnormal T cell differentiation_Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198
• heterogeneous nuclear ribonucleoprotein L
  http://metadb.riken.jp/db/mgi_rdf/MGI:104816
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Hnrnpl<tm1.1Tmo>|Tg(Lck-cre)548Jxm|Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell differentiation
  http://purl.obolibrary.org/obo/MP_0002145

文献

http://purl.org/net/cito/citesAsAuthority

• Marie-Claude. Gaudreau, et.al., Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L regulates development, proliferation, and migration of thymic pre-T cells., Journal of immunology (Baltimore, Md. : 1950), 2012, 188
  http://rdf.ncbi.nlm.nih.gov/pubmed/22523384