Marie-Claude. Gaudreau, et.al., Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L regulates development, proliferation, and migration of thymic pre-T cells., Journal of immunology (Baltimore, Md. : 1950), 2012, 188

http://rdf.ncbi.nlm.nih.gov/pubmed/22523384

Marie-Claude. Gaudreau, et.al., Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L regulates development, proliferation, and migration of thymic pre-T cells., Journal of immunology (Baltimore, Md. : 1950), 2012, 188

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hnrnpl<tm1.1Tmo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5442362
• Hnrnpl<tm1.2Tmo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5442363

class

http://purl.org/net/cito/citesAsAuthority

• Hnrnpl<tm1.1Tmo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5442362
• Hnrnpl<tm1.2Tmo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5442363

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thymus hypoplasia_Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0001823B6CgHnrnpltm11TmoTgLckcre548JxmHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0TgLckcre548JxmHnrnpltm11Tmo
• abnormal T cell differentiation_Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0002145B6CgHnrnpltm11TmoTgLckcre548JxmHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0TgLckcre548JxmHnrnpltm11Tmo
• abnormal T cell differentiation_Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0002145I129S1Sv129X1SvJC57BL6CBAGtROSA26Sortm4ACTBtdTomatoEGFPLuoGtROSA26SorHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0GtROSA26SorHnrnpltm11TmoTgLckcre548JxmGtROSA26Sortm4ACTBtdTomatoEGFPLuo
• decreased T cell number_Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005018B6CgHnrnpltm11TmoTgLckcre548JxmHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0TgLckcre548JxmHnrnpltm11Tmo
• increased double-negative T cell number_Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005090B6CgHnrnpltm11TmoTgLckcre548JxmHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0TgLckcre548JxmHnrnpltm11Tmo
• decreased double-positive T cell number_Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005092B6CgHnrnpltm11TmoTgLckcre548JxmHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0TgLckcre548JxmHnrnpltm11Tmo
他4件を見る
• increased T cell proliferation_Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005348B6CgHnrnpltm11TmoTgLckcre548JxmHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0TgLckcre548JxmHnrnpltm11Tmo
• decreased CD4-positive, alpha beta T cell number_Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008075B6CgHnrnpltm11TmoTgLckcre548JxmHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0TgLckcre548JxmHnrnpltm11Tmo
• decreased CD8-positive, alpha-beta T cell number_Hnrnpl<tm1.1Tmo>/Hnrnpl<tm1.1Tmo>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008079B6CgHnrnpltm11TmoTgLckcre548JxmHnrnpltm11TmoHnrnpltm11TmoTgLckcre548Jxm0TgLckcre548JxmHnrnpltm11Tmo
• embryonic lethality before implantation, complete penetrance_Hnrnpl<tm1.2Tmo>/Hnrnpl<tm1.2Tmo>
  http://metadb.riken.jp/0011094IC57BL6Hnrnpltm12TmoHnrnpltm12TmoHnrnpltm12Tmo