no abnormal phenotype detected_Gt(ROSA)26Sor<tm1.1(CAG-COX8A/Dendra2)Dcc>/Gt(ROSA)26Sor<+>,Mfn1<tm2Dcc>/Mfn1<tm2Dcc>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>

http://metadb.riken.jp/0002169I129129S6SvEvTacC57BL6JSJLJGtROSA26Sortm11CAGCOX8ADendra2DccGtROSA26SorMfn1tm2DccMfn1tm2DccSlc6a3tm11creBkmnSlc6a3Slc6a3Mfn1tm2DccGtROSA26SorGtROSA26Sortm11CAGCOX8ADendra2DccSlc6a3tm11creBkmn

no abnormal phenotype detected_Gt(ROSA)26Sor<tm1.1(CAG-COX8A/Dendra2)Dcc>/Gt(ROSA)26Sor<+>,Mfn1<tm2Dcc>/Mfn1<tm2Dcc>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• mitofusin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914664
• solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:94862

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1.1(CAG-COX8A/Dendra2)Dcc>/Gt(ROSA)26Sor<+>,Mfn1<tm2Dcc>/Mfn1<tm2Dcc>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc6a3<+>|Mfn1<tm2Dcc>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1.1(CAG-COX8A/Dendra2)Dcc>|Slc6a3<tm1.1(cre)Bkmn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S6/SvEvTac * C57BL/6J * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• no abnormal phenotype detected
  http://purl.obolibrary.org/obo/MP_0002169

文献

http://purl.org/net/cito/citesAsAuthority

• Anh H. Pham, et.al., Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit., Human molecular genetics, 2012, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/22859504