decreased brain weight_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0

http://metadb.riken.jp/0002175IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd

decreased brain weight_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 6799, Robert Vassar
  http://metadb.riken.jp/db/mgi_rdf/MGI:3693207
• transgene insertion 30, Katharina Schindowski
  http://metadb.riken.jp/db/mgi_rdf/MGI:4940069

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas|Tg(Thy1-MAPT*)30Schd

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased brain weight
  http://purl.obolibrary.org/obo/MP_0002175

文献

http://purl.org/net/cito/citesAsAuthority

• Céline. Héraud, et.al., Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice., Neurobiology of disease, 2014, 62
  http://rdf.ncbi.nlm.nih.gov/pubmed/24076100